据卡雷尔·曼德，Mostaert出生在哈莱姆，并已雅各面包车哈勒姆的学生，即在绘有承运人的公会祭坛的画家街 Bavochurch。他英俊，口才和礼貌，并自称是从的哈勒姆骑士后裔远征到达米埃塔。他工作18年作为肖像画家奥地利的玛格丽特（1480年至1530年），巡抚哈布斯堡荷兰。他在安特卫普，在那里他被授予终身养老金死亡。Mostaert的名字第一次出现在城市的记录于1498年，他娶了一年，在他的出生地买了一套房子。他也是在哈勒姆的档案中提到，从1527到1554在1500 Mostaert委托绘制百叶窗的插座外壳的遗物圣徒在格鲁特教堂，哈勒姆。从这日起，他开始在的记录，上市圣卢克哈勒姆协会，并继续频繁上市，直到1549年，他在1507年成为了画家的公会的执事，又在1543和1544。

Mostaert的老师雅各布面包车哈勒姆可能实际上是匿名的不伦瑞克双连画大师。卡雷尔·曼德详细描述了几部作品，包括他的西印度群岛的奇特景观，他认为这是一个未完成的工作。大部分Mostaert的工作毁于哈勒姆的大火于1576年，如今一旦归因于他一些画是由于迪恩Isenbrant。

他最早的作品受到明显影响海特亨·托特·信·扬斯，较早的哈勒姆艺术家。一些人认为，Mostaert实际上学徒Geertgen，但令人怀疑的是，艺术家在职业生涯中有过任何学徒或车间助理。从Geertgen，Mostaert采用了精致的风格和周到的成分为他的作品，以及他的人物的生硬，棱角分明的外观。

与1510和1516 Mostaert开发出了细腻的风格，他的玩偶形象在他居住的亮蓝色天空的风景，例如朝拜的贤士（约1520至25年）。他的笔触精致精确，用一种近乎宗教对细节的关注。另外值得注意的是风景，这表明他对倾向与广阔的丘陵更浪漫景致。在1520年代Mostaert也受到影响约阿希姆Patinir的取山水。Mostaert的圣 克里斯托弗，与拥有河流后退到一个广阔的丘陵背景景观画，有一次甚至归因于Patinir。

Mostaert的这一前期的肖像作品包括一件名为阿贝尔范登Coulster的肖像（约1500-10），其中一个优雅，轻薄脸的男人坐落在同样优雅的环境。Mostaert被称为复制原始人像他的一些宫廷佣金，但为的是与案件肖像亚伯，他还画从生活中的数字并添加贵族风格。他被称为在三季度长介绍他的肖像保姆，并把他们的手放在垫子。

作为一个有成就的宫廷画家允许Mostaert谋生了他的艺术，并获得稳定的惠顾。最后的记录提到他是在1549年，当他请求为住在许可哈勒姆镇议会霍伦，以便他能完成一个祭坛那里。

According to Karel Mander, Mostaert was born in Harlem, and has been a student of James Van Haarlem, that is, in the drawing of the union of the carrier of the painter's street Bavochurch. [1] he is handsome, eloquent and polite, and claimed to be descended from the Knights of Haarlem expedition to damietta. [1] he worked for 18 years as a portrait painter Margaret of Austria (1480 to 1530), the governor of the Habsburg Holland. [1] he died in Antwerp, where he was granted a lifetime pension. [1] Mostaert's name first appeared in the city's record in 1498, and he married a year in his birthplace to buy a house. He is also mentioned in the archives of Haarlem, from 1527 to 1554 in the socket shell 1500 Mostaert shutters commissioned to paint the remains of the saint in Grote church, Haarlem. From that day on, he began to record, listed on the Haarlem guild of St. Luke, and continue to frequent listing, until 1549, he became a painter of the deacon of the guild in 1507, and in 1543 and 1544.
Mostaert's teacher Jacob van Haarlem may actually be an anonymous Brunswick double painting master. Karel Mander described several works, including his peculiar landscape of the West Indies, he believes that this is an unfinished work. Most of Mostaert's work destroyed by fire in Haarlem in 1576, now once attributed to him some pictures by Dean Isenbrant.
His earliest work was obviously influenced by Heitgen Toth Sin Jans, an early Haarlem artist. Some people think that Mostaert actually apprenticed to Geertgen, but it is doubtful that artists have had any apprenticeship or workshop assistants in their careers. From Geertgen, Mostaert uses a refined style and thoughtful compositions for his work, as well as the blunt, angular appearance of his characters.
With 1510 and 1516 Mostaert developed a delicate style, his doll image he lives in bright blue sky scenery, such as the worship of the Magi (about 1520 to 25 years). His strokes are exquisite and precise, with a near religious attention to detail. It is also worth noting that the scenery, which shows that he has a more romantic view of the tendency and broad hills. In 1520s Mostaert was also affected by Joachim's Patinir landscape. Mostaert's San Christopher, with a landscape painting with a river receding back into a broad hill, once even attributed to Patinir.
Mostaert's portrait of this earlier period includes a portrait of Abel van den Coulster (about 1500-10), in which an elegant, thin faced man is situated in the same elegant environment. Mostaert is known to reproduce the original portrait of some of his court commissions, but for the sake of the portrait of the case with Abe, he also painted figures from life and added aristocratic style. He was called in the three quarter long portrait of his nanny, and put their hands on the mat.
As an accomplished court painter allowed Mostaert to earn a living for his art, and to obtain steady patronage. The last record referred to him in 1549, when he asked for permission to live in the town council of Haarlem, so that he could complete an altar there.