出生于卡斯特圣乔瓦尼，今天圣乔万尼达诺，于1401年12月21日，乔万尼MONE开赛公证和他的妻子Jacopa迪Martinozzo的儿子。开赛姓氏来自于活动的马萨乔的父系家族从事的名字：他们是橱柜（在意大利，开赛）。1406年，随着结婚，乔瓦尼的第二个孩子的出生重合 ， 然后收到绰号“ Scheggia ” - ，死了父亲。母亲改嫁到香料商人德语迪马斯特罗迪菲奥，也是一个鳏夫，有两个女儿，谁在1417年8月7日死亡。

马萨乔迁至佛罗伦萨之间的1417年和1421年，也许是因为他的继父去世的。有有显示，马萨乔的母亲在这个城市租了房子，在圣尼可罗马基奥尔特拉诺的区文件，肯定喜欢的房子为她的儿子，当她继续给住在她已故的丈夫回家。这是可能的，年轻的艺术家开始了他的职业生涯在佛罗伦萨的车间Bicci迪洛伦佐或别人。在1422年1月7，他就读于医疗和香料的艺术（工会），这表明行使，作为一个城市的自由画家阿诺。

他的第一个安全的工作是三联的圣朱韦纳尔去中科院自动化所，负有日，在中央台，1422年4月23：公元MCCCCXXII一个Ventitre DI D'AP [RILE] 。这是可能的，根据意味着瓦萨里，在1423马萨乔进行了一趟罗马，以纪念五十周年。1424年，他报名参加了公司佛罗伦萨圣·卢卡斯。今年还是在1425可能开始与合作Masolino新鲜的教堂布兰卡契小堂的圣母胭脂红在那个城市。在1426年2月开始的比萨polyptych，工作是会占据他大部分的一年。

1428，他移居罗马，白兰度枢机主教邀请给郎世宁装饰圣克莱门特教堂在同名教堂。在罗马，他曾在圣玛丽重大，它保留了“圣徒杰罗姆和约翰祭坛的浸信会”（在现在国家美术馆的伦敦）。他在罗马去世的1428秋天，当时他年仅20岁。一些旧的来源提及，他被毒死的传闻。
 

Custer was born in St. Giovanni, today San Giovanni Dano, on December 21, 1401, the start of MONE Giovanni notary and his wife Jacopa di Martinozzo son. Start from the activities of the surname of Masaccio patrilineal family name: they are engaged in the cabinet (in Italy start). In 1406, with the birth of Giovanni, the birth of the second children were coincident, and then received the nickname "Scheggia" - the dead father. His mother remarried to Dimas Tero Diffie and German spice merchants Austria, a widower, has two daughters, who died in August 7, 1417.
Between 1417 and Felipe moved to Florence in 1421, perhaps because his stepfather died. There is a display, the mother of Masaccio rented a house in the city, in the holy house of Niccolo Markey Oort file, must love the house for her son, as she continued to live in her late husband home. It is possible that the young artist began his career in the workshop of Florence Bicci di Lorenzo or others. In January 1422 7, he enrolled in the art of medicine and spices (trade union), which shows the exercise, as a city of freelance painter Arno.
His first job is to triple safety San Zhu Wei NAR to Institute of automation, has, in Central Taiwan, April 1422 23: a Ventitre DI D'AP in MCCCCXXII [RILE]. It is possible that means according to Vasari, in 1423 by Masaccio on a trip to Rome to commemorate the fifty anniversary. In 1424, he enrolled in the Florence Sasan Lucas company. This year or in 1425 may begin collaboration with Masolino fresh church brancacci Chapel of the virgin carmine in the city. Starting in February 1426, pizza polyptych, work will occupy most of his year.
In 1428, he moved to Rome, cardinal Brando Lang Shining invited to decorate the Church of St. Clement Church in the same name. In Rome, he worked at St. Mary's major, it retains the "Baptist Saint Jerome and John altar" (now The National Gallery in London). He died in Rome in the fall of 1428, when he was only 20 years old. Mention some of the old sources, he was poisoned by rumors.